CCL20/MIP-3 alpha Rekombinanter Antikörper

CCL20/MIP-3 alpha Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241694B4

Kat-Nr. : 84413-3-PBS

Synonyme

CCL20, MIP-3 Alpha, MIP-3α, 241694B4, Beta-chemokine exodus-1

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  WB analysis using 84413-3-RR (same clone as 84413-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84413-3-RR (CCL20/MIP-3 alpha antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84413-3-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 84413-3-RR (same clone as 84413-3-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 84413-3-RR (CCL20/MIP-3 alpha antibody) at dilution of 1:2500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84413-3-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon using 84413-3-RR (same clone as 84413-3-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 84413-3-RR (CCL20/MIP-3 alpha antibody) at dilution of 1:2500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84413-3-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

84413-3-PBS bindet in WB, IHC, Indirect ELISA CCL20/MIP-3 alpha und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CCL20/MIP-3 alpha fusion protein Eg2398
• Vollständiger Name: chemokine (C-C motif) ligand 20
• Berechnetes Molekulargewicht: 11kDa
• Beobachtetes Molekulargewicht: 11 kDa
• GenBank-Zugangsnummer: NM_004591.3
• Gene symbol: CCL20/MIP-3 alpha
• Gene ID (NCBI): 6364
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CCL20, also known as macrophage infiltrating factor protein 3α, is a C-C chemokine that specifically binds to the receptor CCR6. CCL20 is produced in various tissues and by a wide range of immune cells, including neutrophils, natural killer cells, T-helper type 17 (Th17) cells, B cells, and various antigen-presenting cells, such as dendritic cells (DCs), Langerhans cells, and macrophages. Increased expression of CCL20 is likely involved in the increased recruitment of dendritic cells observed in fibroinflammatory diseases such as chronic obstructive pulmonary disease (COPD). CCL20 expression is increased by the proinflammatory cytokine IL-1 beta.