CCL24/Eotaxin 2 Rekombinanter Antikörper

CCL24/Eotaxin 2 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

243063C9

Kat-Nr. : 98476-3-PBS

Synonyme

CCL24, Eotaxin 2, C C motif chemokine 24, C-C motif chemokine 24, CCL 24

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  FC experiment of Transfected HEK-293T using 98476-3-RR (same clone as 98476-3-PBS)

  1x10^6 HEK-293T cells (left) or CCL24/Eotaxin 2-transfected HEK-293T cells (right) were intracellularly stained with 0.2 ug Anti-Human CCL24/Eotaxin 2 Rabbit RecAb (98476-3-RR, Clone: 243063C9) and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98476-3-PBS in a different storage buffer formulation.

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  FC experiment of Transfected HEK-293T using 98476-3-RR (same clone as 98476-3-PBS)

  1x10^6 HEK-293T cells (left) or CCL24/Eotaxin 2-transfected HEK-293T cells (right) were intracellularly stained with 0.2 ug Anti-Human CCL24/Eotaxin 2 Rabbit RecAb (98476-3-RR, Clone: 243063C9) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98476-3-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98476-3-PBS bindet in FC CCL24/Eotaxin 2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CCL24/Eotaxin 2 fusion protein Eg0395
• Vollständiger Name: chemokine (C-C motif) ligand 24
• Berechnetes Molekulargewicht: 13kd
• GenBank-Zugangsnummer: NM_002991
• Gene symbol: CCL24/Eotaxin 2
• Gene ID (NCBI): 6369
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Chemokine CCL24 is the second member of eotaxins, a group of eosinophils' selectively chemoattractants. CCL24 is constitutively expressed in fibroblasts, epithelial cells, macrophages. CCL24 has only one receptor CCR3, which mainly presents on eosinophils and was also found on basophils, monocytes, Th2 lymphocytes, epithelial cells and airway smooth muscles. CCL24 displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes.