CCL3/MIP-1 alpha Rekombinanter Antikörper

CCL3/MIP-1 alpha Rekombinant Antikörper für IF/ICC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

IF/ICC, ELISA

Konjugation

Unkonjugiert

CloneNo.

241695B10

Kat-Nr. : 84701-1-RR

Synonyme

241695B10, C-C motif chemokine 3, Ccl3, Heparin-binding chemotaxis protein, L2G25B

---

• 

  IF Staining of RAW 264.7 using 84701-1-RR

  Immunofluorescent analysis of (4% PFA) fixed RAW 264.7 cells using CCL3 antibody (84701-1-RR, Clone: 241695B10 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2).

• 

  Affinity and Kinetic Characterization of 84701-1-RR

  Biolayer interferometry (BLl) kinetic assays of 84701-1-RR against Mouse CCL3 were performed. The affinity constant is 4.00 nM.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in IF/ICC: RAW 264.7-Zellen

Empfohlene Verdünnung

• Immunfluoreszenz (IF)/ICC: IF/ICC : 1:200-1:800

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

84701-1-RR bindet in IF/ICC, ELISA CCL3/MIP-1 alpha und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CCL3/MIP-1 alpha fusion protein Eg2170
• Vollständiger Name: chemokine (C-C motif) ligand 3
• Berechnetes Molekulargewicht: 10kd
• GenBank-Zugangsnummer: NM_011337
• Gene symbol: Ccl3
• Gene ID (NCBI): 20302
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CCL3, also known as macrophage inflammatory protein-1 alpha (MIP-1α), is a chemokine that plays a significant role in immune responses. It is involved in recruiting immune cells, particularly monocytes and T cells, to sites of inflammation and infection. CCL3 is produced by various cell types, including activated macrophages and lymphocytes, and is crucial for orchestrating the immune response to infections and tissue injury. In summary, CCL3 is a multifunctional chemokine that is essential for immune cell recruitment and plays a role in various diseases, including chronic inflammatory conditions and cancer.