CCL4/MIP-1 beta Polyklonaler Antikörper

CCL4/MIP-1 beta Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22352-1-PBS

Synonyme

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  WB analysis using 22352-1-AP (same clone as 22352-1-PBS)

  Untreated, PMA, LPS, and Brefeldin A treated THP-1 cells were subjected to SDS PAGE followed by western blot with 22352-1-AP (CCL4/MIP-1 beta antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22352-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

22352-1-PBS bindet in WB, Indirect ELISA CCL4/MIP-1 beta und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CCL4/MIP-1 beta fusion protein Ag17928
• Vollständiger Name: chemokine (C-C motif) ligand 4
• Berechnetes Molekulargewicht: 92 aa, 10 kDa
• Beobachtetes Molekulargewicht: 11 kDa
• GenBank-Zugangsnummer: BC107433
• Gene symbol: CCL4/MIP-1 beta
• Gene ID (NCBI): 6351
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CCL4, also known as Macrophage inflammatory protein-1β (MIP-1β), is a CC chemokine with specificity for CCR5 receptors, and is one of the major HIV-suppressive factors produced by CD8+ T-cells. MIP-1β is an acidic protein composed of 69 amino acids that is produced by many cells, particularly macrophages, dendritic cells, and lymphocytes. MIP-1β is responsible for the activation of PMN and is involved in acute neutrophilic inflammation. Recombinant MIP-1β induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).