CCNL1 Polyklonaler Antikörper
CCNL1 Polyklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 13138-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
13138-1-PBS bindet in WB, Indirect ELISA CCNL1 und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | CCNL1 fusion protein Ag3731 |
| Vollständiger Name | cyclin L1 |
| Berechnetes Molekulargewicht | 526 aa, 60 kDa |
| Beobachtetes Molekulargewicht | 46 kDa |
| GenBank-Zugangsnummer | BC007081 |
| Gene symbol | CCNL1 |
| Gene ID (NCBI) | 57018 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
CCNL1, also named as Cyclin-L1, contains a RS region and belongs to the cyclin family. CCNL1 localizes in the nucleus speckle and is Overexpressed in primary tumors of head and neck squamous cell carcinomas (HNSCC). CCNL1 as transcriptional regulator participates in regulating the pre-mRNA splicing process. It is seems to be involved in the regulation of RNA polymerase II (pol II). CCNL1 functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. It may be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). The calculated molecular weight of CCNL1 is about 55-60 kDa, but we detected a 40-50 kDa isoform by western blotting.



