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CCNL2 Polyklonaler Antikörper

CCNL2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11212-1-PBS

Synonyme

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  • Western Blot (WB) analysis of various lysates using CCNL2 Polyclonal antibody (11212-1-AP)

    WB analysis using 11212-1-AP (same clone as 11212-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11212-1-AP (CCNL2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11212-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of A375 cells using CCNL2 Polyclonal antibody (11212-1-AP)

    WB analysis of A375 using 11212-1-AP (same clone as 11212-1-PBS)

    WB result of CCNL2 antibody (11212-1-AP; 1:800; incubated at room temperature for 1.5 hours) with sh-Control and sh-CCNL2 transfected A375 cells. This data was developed using the same antibody clone with 11212-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

11212-1-PBS bindet in WB, Indirect ELISA CCNL2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CCNL2 fusion protein Ag1710
Vollständiger Name cyclin L2
Berechnetes Molekulargewicht 58 kDa
Beobachtetes Molekulargewicht 28 kDa
GenBank-ZugangsnummerBC016333
Gene symbol CCNL2
Gene ID (NCBI) 81669
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CCNL2 (Cyclin-L2) is also named as SB138 and Paneth cell-enhanced expression protein. Human cyclin L2 is a novel member of the cyclin family. Human cyclin L2 shares significant homology to cyclin L1, K, T1, T2, and C, which are involved in transcriptional regulation via phosphorylation of the C-terminal domain of RNA polymerase II (PMID: 14684736). Cyclin L2 co-localizes with splicing factors SC-35 and 9G8 within nuclear speckles and that it associates with hyperphosphorylated, but not hypophosphorylated, RNA polymerase II and CDK p110 PITSLRE kinase via its N-terminal cyclin domains (PMID: 14684736). Human cyclin L2 is expressed ubiquitously in normal human tissues and tumor cells.