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CCR2a-specific Rekombinanter Antikörper

CCR2a-specific Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242217G4

Kat-Nr. : 84911-3-PBS

Synonyme

CCR2, 242217G4, C C chemokine receptor type 2, C C CKR 2, C-C chemokine receptor type 2

Filter:
  • Western Blot (WB) analysis of various lysates using CCR2a-specific Recombinant antibody (84911-3-RR)

    WB analysis using 84911-3-RR (same clone as 84911-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84911-3-RR (CCR2a-specific antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84911-3-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of THP-1 cells using CCR2a-specific Recombinant antibody (84911-3-RR)

    IF Staining of THP-1 using 84911-3-RR (same clone as 84911-3-PBS)

    Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using CCR2a-specific antibody (84911-3-RR, Clone: 242217G4 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84911-3-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84911-3-PBS bindet in WB, IF/ICC, Indirect ELISA CCR2a-specific und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name chemokine (C-C motif) receptor 2
Berechnetes Molekulargewicht 42 kDa
Beobachtetes Molekulargewicht35 kDa
GenBank-ZugangsnummerNM_000647
Gene symbol CCR2
Gene ID (NCBI) 729230
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CCR2 encodes a receptor for MCP1, functioning in inflammatory processes, tumor infiltration, and monocyte invasion of artery walls in atherosclerosis. There are two isoforms of CCR2, CCR2A and CCR2B. CCR2 isoforms were expressed by different cell subsets in both normal and IIM muscle. CCR2A was expressed in vessel walls and by some mononuclear cells, especially in cells involved in partial invasion in PM and IBM. CCR2B expression was observed in all satellite cells, in the muscular domain of neuromuscular junctions, and in some regenerative fibers of IIM, but not in inflammatory exudates.