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CCR3 Rekombinanter Antikörper

CCR3 Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250209D5

Kat-Nr. : 86038-1-PBS

Synonyme

C C chemokine receptor type 3, C C CKR 3, C C CKR3, C-C chemokine receptor type 3, CC CKR 3

Filter:
  • Western Blot (WB) analysis of various lysates using CCR3 Recombinant antibody (86038-1-RR)

    WB analysis using 86038-1-RR (same clone as 86038-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86038-1-RR (CCR3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86038-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of K-562 cells using CCR3 Recombinant antibody (86038-1-RR)

    IF Staining of K-562 using 86038-1-RR (same clone as 86038-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed K-562 cells using CCR3 antibody (86038-1-RR, Clone: 250209D5 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 86038-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86038-1-PBS bindet in WB, IF/ICC, Indirect ELISA CCR3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name chemokine (C-C motif) receptor 3
Berechnetes Molekulargewicht 355 aa, 41 kDa
Beobachtetes Molekulargewicht53 kDa
GenBank-ZugangsnummerBC110297
Gene symbol CCR3
Gene ID (NCBI) 1232
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CCR3 (C-C Motif Chemokine Receptor 3), also known as CD193, is a G protein-coupled receptor (GPCR) primarily involved in immune cell trafficking and inflammation regulation and highly expressed in eosinophils and basophils, with detectable levels in Th2 cells, airway epithelial cells, and subsets of monocyte-derived dendritic cells (PMID: 21077277). Ligand-induced CCR3 internalization is required for eosinophil shape change and actin polymerization but not for calcium mobilization or desensitization (PMID: 12532103).