Neprilysin/CD10 Rekombinanter Antikörper
Neprilysin/CD10 Rekombinant Antikörper für FC
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
FC
Konjugation
Unkonjugiert
CloneNo.
241322E1
Kat-Nr. : 98116-1-RR
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in FC | human peripheral blood leukocytes, Reh cells |
Empfohlene Verdünnung
Anwendung | Verdünnung |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Produktinformation
98116-1-RR bindet in FC Neprilysin/CD10 und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | Rekombinantes Protein |
Vollständiger Name | membrane metallo-endopeptidase |
Berechnetes Molekulargewicht | 750 aa, 86 kDa |
GenBank-Zugangsnummer | BC101658 |
Gene symbol | CD10 |
Gene ID (NCBI) | 4311 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein A purfication |
Lagerungspuffer | PBS with 0.09% sodium azide |
Lagerungsbedingungen | Store at 2 - 8°C. Stable for one year after shipment. |
Hintergrundinformationen
CD10, also known as neprilysin, membrane metallo-endopeptidase (MME), neutral endopeptidase (NEP), or common acute lymphoblastic leukemia antigen (CALLA), is a 100-kDa type II transmembrane glycoprotein belonging to peptidase M13 family (PMID: 7760013; 8102558). Among hematopoietic cells, CD10 is expressed on granulocytes, B cell precursors, mature germinal center B cells, a subset of immature thymocytes (PMID: 13679451). CD10 is also expressed on a variety of nonhematopoietic cell types, including bronchial epithelial cells, cultured fibroblasts, bone marrow stromal cells, renal proximal tubular epithelial cells, breast myoepithelium, biliary canaliculi (PMID: 8102558). CD10 is a cell surface peptidase that cleaves peptide bonds on the amino side of hydrophobic amino acids and inactivates a variety of physiologically active peptides. Loss or decreases in CD10 expression have been reported in a variety of malignancies (PMID: 16054017).
Protokolle
PRODUKTSPEZIFISCHE PROTOKOLLE | |
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FC protocol for Neprilysin/CD10 antibody 98116-1-RR | Download protocol |
STANDARD-PROTOKOLLE | |
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Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |