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CD100 Rekombinanter Antikörper

CD100 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241709G4

Kat-Nr. : 84465-5-PBS

Synonyme

SEMA4D, SEM4D, CD100 antigen, CD 100, A8

Filter:
  • Western Blot (WB) analysis of Daudi cells using CD100 Recombinant antibody (84465-5-RR)

    WB analysis of Daudi using 84465-5-RR (same clone as 84465-5-PBS)

    Daudi cells were subjected to SDS PAGE followed by western blot with 84465-5-RR (CD100 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84465-5-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84465-5-PBS bindet in WB, Indirect ELISA CD100 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
Berechnetes Molekulargewicht 96 kDa
Beobachtetes Molekulargewicht150 kDa
GenBank-ZugangsnummerBC054500
Gene symbol SEMA4D/CD100
Gene ID (NCBI) 10507
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD100 (also known as SEMA4D), a 150 kDa homodimer, belongs to the family of immune semaphorins, and CD100 is abundantly expressed on resting T cells, NK cells, and antigen-presenting cells. As a transmembrane glycoprotein, it is digested to its soluble form, sCD100, by specific matrix metalloproteinases. CD100 has been reported that the expression levels of CD100, and one of its receptors, plexin-B1 (PLXNB1), are increased in head and neck, prostate, colon, breast, and lung cancers, and the interaction between them provides oncogenic signaling essential for tumor growth and metastasis.