CD106 Monoklonaler Antikörper

CD106 Monoklonal Antikörper für FC

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

FC

Konjugation

PE Fluorescent Dye

CloneNo.

1.G11B1

Kat-Nr. : PE-65049

Synonyme

CD106, DKFZp779G2333, INCAM 100, V CAM 1, VCAM 1, VCAM1

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Galerie der Validierungsdaten

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  FC experiment of HUVEC using PE-65049

  1X10^6 TNF-α stimulated HUVEC cells were surface stained with 10 ul PE Anti-Human CD106 (PE-65049, Clone:1.G11B1) (red) or PE-mouse IgG1 isotype control (black). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: HUVEC-Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 10 µl per 10^6 cells in a 100 µl suspension or 10 µl per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

PE-65049 bindet in FC CD106 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: vascular cell adhesion molecule 1
• Berechnetes Molekulargewicht: 739 aa, 81 kDa
• GenBank-Zugangsnummer: BC017276
• Gene symbol: VCAM1
• Gene ID (NCBI): 7412
• Konjugation: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: PBS mit 0,1% Natriumazid und einem Stabilisator.
• Lagerungsbedingungen: Bei 2-8°C lagern. Vor Licht schützen. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Vascular cell adhesion molecule 1 (VCAM1), also known as CD106, is a 110-kDa transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium, interacts with integrin VLA4 (α4β1) present on the surface of leukocytes, and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types, including vascular smooth muscle cells, differentiating skeletal muscle cells, renal and neural epithelial cells, macrophages (Kupffer cells), dendritic cells, and bone marrow stromal cells (PMID: 7507076, 11359843).