CD117/c-Kit Monoklonaler Antikörper
CD117/c-Kit Monoklonal Antikörper für FC
Wirt / Isotyp
Ratte / IgG2b, kappa
Getestete Reaktivität
Maus
Anwendung
FC
Konjugation
PE Fluorescent Dye
CloneNo.
2B8
Kat-Nr. : PE-65054
Synonyme
Geprüfte Anwendungen
| Erfolgreiche Detektion in FC | Maus-Knochenmarkzellen |
Empfohlene Verdünnung
| Anwendung | Verdünnung |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Produktinformation
PE-65054 bindet in FC CD117/c-Kit und zeigt Reaktivität mit Maus
| Getestete Reaktivität | Maus |
| Wirt / Isotyp | Ratte / IgG2b, kappa |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | Maus IL-3-abhängige Knochenmark-Mastzellen |
| Vollständiger Name | kit oncogene |
| GenBank-Zugangsnummer | BC052457 |
| Gene symbol | CD117 |
| Gene ID (NCBI) | 16590 |
| Konjugation | PE Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 496 nm, 565 nm / 578 nm |
| Form | Liquid |
| Reinigungsmethode | Affinitätsreinigung |
| Lagerungspuffer | PBS with 0.09% sodium azide |
| Lagerungsbedingungen | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Hintergrundinformationen
CD117, also known as c-Kit and SCFR, is a transmembrane protein with tyrosine kinase activity encoded by the oncogene c-kit (PMID: 2448137). It is a member of the type III receptor tyrosine kinase family, which also includes CSF-1R, PDGFRβ, PDGFRα, and FLT3 (PMID: 29518044). CD117 is expressed on hematopoietic stem cells and progenitor cells, mast cells, and is also found in a wide range of non-haemopoietic cell types (including melanocytes, germ cells, astrocytes, renal tubules, breast glandular epithelial cells, sweat glands, and interstitial cells of Cajal) (PMID: 10582338; 23073628). CD117 plays an important role in early haemopoiesis. It is also involved in pigmentation, fertility, gut movement, and some aspects of the nervous system (PMID: 23073628).
Protokolle
| PRODUKTSPEZIFISCHE PROTOKOLLE | |
|---|---|
| FC protocol for PE CD117/c-Kit antibody PE-65054 | Download protocol |
| STANDARD-PROTOKOLLE | |
|---|---|
| Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |
