CD117/c-Kit Rekombinanter Antikörper
CD117/c-Kit Rekombinant Antikörper für FC
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
FC
Konjugation
Unkonjugiert
CloneNo.
241313C5
Kat-Nr. : 98377-1-RR
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in FC | TF-1-Zellen, FC receptor blocked human blood cells |
Empfohlene Verdünnung
Anwendung | Verdünnung |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Produktinformation
98377-1-RR bindet in FC CD117/c-Kit und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | Rekombinantes Protein |
Vollständiger Name | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
Berechnetes Molekulargewicht | 976 aa, 110 kDa |
GenBank-Zugangsnummer | BC071593 |
Gene symbol | CD117 |
Gene ID (NCBI) | 3815 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein A purfication |
Lagerungspuffer | PBS with 0.09% sodium azide |
Lagerungsbedingungen | Store at 2 - 8°C. Stable for one year after shipment. |
Hintergrundinformationen
CD117, also known as c-Kit and SCFR, is a transmembrane protein with tyrosine kinase activity encoded by the oncogene c-kit (PMID: 2448137). It is a member of the type III receptor tyrosine kinase family, which also includes CSF-1R, PDGFRβ, PDGFRα, and FLT3 (PMID: 29518044). CD117 is expressed on hematopoietic stem cells and progenitor cells, mast cells, and is also found in a wide range of non-haemopoietic cell types (including melanocytes, germ cells, astrocytes, renal tubules, breast glandular epithelial cells, sweat glands, and interstitial cells of Cajal) (PMID: 10582338; 23073628). CD117 plays an important role in early hemopoiesis. It is also involved in pigmentation, fertility, gut movement, and some aspects of the nervous system (PMID: 23073628).
Protokolle
PRODUKTSPEZIFISCHE PROTOKOLLE | |
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FC protocol for CD117/c-Kit antibody 98377-1-RR | Download protocol |
STANDARD-PROTOKOLLE | |
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Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |