CD117/c-Kit Rekombinanter Antikörper

CD117/c-Kit Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241313C5

Kat-Nr. : 98377-1-RR

Synonyme

CD117, KIT, C Kit, c-Kit, EC:2.7.10.1



Geprüfte Anwendungen

Erfolgreiche Detektion in FCTF-1-Zellen, FC receptor blocked human blood cells

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98377-1-RR bindet in FC CD117/c-Kit und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Berechnetes Molekulargewicht 976 aa, 110 kDa
GenBank-ZugangsnummerBC071593
Gene symbol CD117
Gene ID (NCBI) 3815
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS with 0.09% sodium azide
LagerungsbedingungenStore at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

CD117, also known as c-Kit and SCFR, is a transmembrane protein with tyrosine kinase activity encoded by the oncogene c-kit (PMID: 2448137). It is a member of the type III receptor tyrosine kinase family, which also includes CSF-1R, PDGFRβ, PDGFRα, and FLT3 (PMID: 29518044). CD117 is expressed on hematopoietic stem cells and progenitor cells, mast cells, and is also found in a wide range of non-haemopoietic cell types (including melanocytes, germ cells, astrocytes, renal tubules, breast glandular epithelial cells, sweat glands, and interstitial cells of Cajal) (PMID: 10582338; 23073628). CD117 plays an important role in early hemopoiesis. It is also involved in pigmentation, fertility, gut movement, and some aspects of the nervous system (PMID: 23073628).

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
FC protocol for CD117/c-Kit antibody 98377-1-RRDownload protocol
STANDARD-PROTOKOLLE
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