CD11a Rekombinanter Antikörper

CD11a Rekombinant Antikörper für FC

Wirt / Isotyp

Ratte / IgG2a

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

M17/4

Kat-Nr. : 65670-1-PBS

Synonyme

Itgal, integrin alpha L, LFA 1

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  FC experiment of mouse thymocytes using 65670-1-TR (same clone as 65670-1-PBS)

  1x10^6 mouse thymocytes were surface stained with 0.5 ug Anti-Mouse CD11a (M17/4) Rat IgG2a RecAb (65670-1-TR, Clone:M17/4) or Rat IgG2a Isotype Control Recombinant Antibody (98427-1-TR, Clone: 250862A1), and FITC anti-Rat IgG2a antibody. Cells were not fixed. This data was developed using the same antibody clone with 65670-1-PBS in a different storage buffer formulation.

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  FC experiment of mouse thymocytes using 65670-1-TR (same clone as 65670-1-PBS)

  1x10^6 mouse thymocytes were surface stained with 0.5 ug Anti-Mouse CD11a (M17/4) Rat IgG2a RecAb (65670-1-TR, Clone: M17/4) (red) or Rat IgG2a Isotype Control Recombinant Antibody (98427-1-TR, Clone: 250862A1) (blue), and FITC anti-Rat IgG2a antibody. Cells were not fixed. This data was developed using the same antibody clone with 65670-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

65670-1-PBS bindet in FC CD11a und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Ratte / IgG2a
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: integrin alpha L
• GenBank-Zugangsnummer: BC145802
• Gene symbol: CD11a
• Gene ID (NCBI): 16408
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).