CD11a Rekombinanter Antikörper

CD11a Rekombinant Antikörper für FC

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Biotin

CloneNo.

TS2/4

Kat-Nr. : Biotin-65563

Synonyme

Leukocyte function-associated molecule 1 alpha chain, Leukocyte adhesion glycoprotein LFA-1 alpha chain, ITGAL, Integrin alpha-L, Integrin alpha L

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  FC experiment of human peripheral blood leukocytes using Biotin-65563

  1x10^6 human peripheral blood leukocytes were unstained or surface stained with 0.25 ug Biotin Anti-Human CD11a (TS2/4) Mouse IgG2a RecAb (Biotin-65563, Clone: TS2/4) and CoraLite®488-conjugated streptavidin. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  FC experiment of human peripheral blood leukocytes using Biotin-65563

  1x10^6 human peripheral blood leukocytes were unstained (blue) or surface stained with 5 ul Biotin Anti-Human CD11a (TS2/4) Mouse IgG2a RecAb (Biotin-65563, Clone: TS2/4) and CoraLite®488-conjugated streptavidin (red). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: human peripheral blood leukocytes

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

Biotin-65563 bindet in FC CD11a und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: HLA-DR CTL-Linie
• Vollständiger Name: integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
• Berechnetes Molekulargewicht: 129 kDa
• GenBank-Zugangsnummer: BC008777
• Gene symbol: CD11a
• Gene ID (NCBI): 3683
• Konjugation: Biotin
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).