• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

CD122/IL-2RB Rekombinanter Antikörper

CD122/IL-2RB Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241677C9

Kat-Nr. : 84389-2-PBS

Synonyme

IL2RB, IL 2RB, IL 2R subunit beta, IL 2 receptor subunit beta, High affinity IL-2 receptor subunit beta

Filter:
  • Western Blot (WB) analysis of various lysates using CD122/IL-2RB Recombinant antibody (84389-2-RR)

    WB analysis using 84389-2-RR (same clone as 84389-2-PBS)

    NK-92 cells were subjected to SDS PAGE followed by western blot with 84389-2-RR (CD122/IL-2RB antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84389-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84389-2-RR

    Affinity and Kinetic Characterization of 84389-2-RR

    Biolayer interferometry (BLl) kinetic assays of 84389-2-RR against Human CD122/IL-2RB were performed. The affinity constant is 32.2 nM.

Geprüfte Anwendungen

Produktinformation

84389-2-PBS bindet in WB, Indirect ELISA CD122/IL-2RB und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name interleukin 2 receptor, beta
Berechnetes Molekulargewicht 551 aa, 61 kDa
Beobachtetes Molekulargewicht70 kDa
GenBank-ZugangsnummerBC025691
Gene symbol IL2RB
Gene ID (NCBI) 3560
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. The beta subunit (IL2RB, also known as CD122 and p75) is involved in receptor mediated endocytosis and transduces the mitogenic signals of nterleukin 2.