CD122/IL-2RB Monoklonaler Antikörper

CD122/IL-2RB Monoklonal Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3A12C7

Kat-Nr. : 60174-1-PBS

Synonyme

IL2RB, 3A12C7, CD122, High affinity IL-2 receptor subunit beta, IL 2 receptor subunit beta

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  WB analysis using 60174-1-Ig (same clone as 60174-1-PBS)

  Untreated and PNGase F-treated lysates of NK-92 cells were subjected to SDS PAGE followed by western blot with 60174-1-Ig (CD122/IL2RB antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60174-1-PBS in a different storage buffer formulation.

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  WB analysis of Recombinant protein using 60174-1-Ig (same clone as 60174-1-PBS)

  Recombinant protein were subjected to SDS PAGE followed by western blot with 60174-1-Ig (IL2RB antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60174-1-PBS in a different storage buffer formulation.

• 

  Cytometric bead array standard curve of MP50451-1

  Cytometric bead array standard curve of MP50451-1, CD122/IL2RB Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60174-3-PBS. Detection antibody: 60174-1-PBS. Standard:Ag3929. Range: 0.098-25 ng/mL.

• 

  Cytometric bead array standard curve of MP50451-2

  Cytometric bead array standard curve of MP50451-2, CD122/IL2RB Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60174-2-PBS. Detection antibody: 60174-1-PBS. Standard:Ag3929. Range: 0.098-50 ng/mL.

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Geprüfte Anwendungen

Produktinformation

60174-1-PBS bindet in WB, Cytometric bead array, Indirect ELISA CD122/IL-2RB und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: CD122/IL-2RB fusion protein Ag3929
• Vollständiger Name: interleukin 2 receptor, beta
• Berechnetes Molekulargewicht: 551 aa, 61 kDa
• Beobachtetes Molekulargewicht: 75 kDa, 61 kDa
• GenBank-Zugangsnummer: BC025691
• Gene symbol: IL2RB
• Gene ID (NCBI): 3560
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. The beta subunit (IL2RB, also known as CD122 and p75) is involved in receptor mediated endocytosis and transduces the mitogenic signals of nterleukin 2.