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CD13 Rekombinanter Antikörper

CD13 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242845B5

Kat-Nr. : 85152-5-PBS

Synonyme

AP-M, Anpep, Aminopeptidase N, Aminopeptidase M, Alanyl aminopeptidase

Filter:
  • Western Blot (WB) analysis of various lysates using CD13 Recombinant antibody (85152-5-RR)

    WB analysis using 85152-5-RR (same clone as 85152-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85152-5-RR (CD13 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85152-5-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85152-5-PBS bindet in WB, Indirect ELISA CD13 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name alanyl (membrane) aminopeptidase
Berechnetes Molekulargewicht110 kDa
Beobachtetes Molekulargewicht150 kDa
GenBank-ZugangsnummerNM_008486.2
Gene symbol Anpep
Gene ID (NCBI) 16790
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD13, also named as APN, ANPEP (aminopeptidase N) or PEPN, is belongs to the peptidase M1 family. CD13 is a heavily glycosylated, ~150-240 kDa, type-II membrane, expressed by most cells of myeloid origin including monocytes, macrophages, granulocytes, and their hematopoietic precursors. It is also abundantly expressed in the brush border of epithelial cells from renal proximal tubules and small intestine, in prostatic epithelial cells, in bile duct canaliculi, in mast cells, and, in some cases, in fibroblasts and smooth muscle cells. CD13 is a multifunctional protein and plays varying roles in cell migration, cell proliferation, cell differentiation and so on. CD13 participates in angiogenesis generating and modulating angiogenic signals, and can be a marker of angiogenic vessels. CD13 is also a pan-myeloid marker, present on mature granulocytes and monocytes. (PMID: 8805662, 10098327, 18603472, 18097955, 17897790, 17888402, 21339174)