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CD134/OX40 Polyklonaler Antikörper

CD134/OX40 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29361-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CD134/OX40 Polyclonal antibody (29361-1-AP)

    WB analysis using 29361-1-AP (same clone as 29361-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29361-1-AP (CD134/OX40 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29361-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

29361-1-PBS bindet in WB, Indirect ELISA CD134/OX40 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CD134/OX40 fusion protein Ag28521
Vollständiger Name tumor necrosis factor receptor superfamily, member 4
Berechnetes Molekulargewicht 29 kDa
Beobachtetes Molekulargewicht50 kDa
GenBank-ZugangsnummerNM_003327
Gene symbol CD134
Gene ID (NCBI) 7293
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD134, also known as OX40 and TNFRSF4, is a member of the TNFR-superfamily of receptors (PMID: 2828930; 9766631). It is a type I transmembrane protein predominantly expressed on activated T cells which include CD4 and CD8 T cells, Th2, Th1, and Th17 cells, as well as regulatory T cells (Tregs) (PMID: 20307208). CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule (PMID: 26215166). CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmune diseases, cancer and infectious disease (PMID: 26215166; 19426222).