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CD155/PVR Rekombinanter Antikörper

CD155/PVR Rekombinant Antikörper für WB, IF/ICC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, IF/ICC, ELISA

Konjugation

Unkonjugiert

CloneNo.

240731B1

Kat-Nr. : 83724-6-PBS

Synonyme

Pvr, Tage4, poliovirus receptor, CD155, 240731B1

Filter:
  • Western Blot (WB) analysis of various lysates using CD155/PVR Recombinant antibody (83724-6-RR)

    WB analysis using 83724-6-RR (same clone as 83724-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83724-6-RR (CD155/PVR antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83724-6-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of RAW 264.7 cells using CD155/PVR Recombinant antibody (83724-6-RR)

    IF Staining of RAW 264.7 using 83724-6-RR (same clone as 83724-6-PBS)

    Immunofluorescent analysis of (4% PFA) fixed RAW 264.7 cells using CD155/PVR antibody (83724-6-RR, Clone: 240731B1 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83724-6-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of RAW 264.7 cells using CD155/PVR Recombinant antibody (83724-6-RR)

    IF Staining of RAW 264.7 using 83724-6-RR (same clone as 83724-6-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed RAW 264.7 cells using CD155/PVR antibody (83724-6-RR, Clone: 240731B1 ) at dilution of 1:1000 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83724-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83724-6-RR

    Affinity and Kinetic Characterization of 83724-6-RR

    Biolayer interferometry (BLl) kinetic assays of 83724-6-RR against Mouse CD155/PVR were performed. The affinity constant is 0.222 nM.

Geprüfte Anwendungen

Produktinformation

83724-6-PBS bindet in WB, IF/ICC, ELISA CD155/PVR und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name poliovirus receptor
Berechnetes Molekulargewicht45 kDa
Beobachtetes Molekulargewicht80 kDa
GenBank-ZugangsnummerNM_027514.2
Gene symbol CD155/PVR
Gene ID (NCBI) 52118
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD155, also known as the poliovirus receptor (PVR) or Necl-5, is one of the nectin-like family members, belonging to the Ca2+ independent immunoglobulin superfamily (IgSF) in cell adhesion molecules (PMID: 37660884). CD155 is a type I transmembrane protein composed of three extracellular immunoglobulin-like domains, a transmembrane domain, and a cytoplasmic tail. It is involved in cell-to-cell and cell-to-ECM adhesion (PMID: 32019260; 11437656). CD155 acts as a ligand for immune receptors, including TIGIT, CD96 and CD226, which are expressed on T cells and NK cells. CD155 interacts with these receptors to modulate immune responses, such as T cell activation and NK cell-mediated cytotoxicity (PMID: 37660884). CD155 serves as the entry receptor for poliovirus and thereby mediates susceptibility to poliovirus infection (PMID: 15034010).