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CD155/PVR Rekombinanter Antikörper

CD155/PVR Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

240731B1

Kat-Nr. : 98077-1-PBS

Synonyme

Pvr, Tage4, poliovirus receptor, CD155, 240731B1

Filter:
  • Flow cytometry (FC) experiment of mouse thymocytes using Anti-Mouse CD155/PVR Rabbit Recombinant Antibody (98077-1-RR)

    FC experiment of mouse thymocytes using 98077-1-RR (same clone as 98077-1-PBS)

    1x10^6 mouse thymocytes were surface stained with 0.25 ug Anti-Mouse CD155/PVR Rabbit Recombinant Antibody (98077-1-RR, Clone:240731B1) or isotype control and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG. Cells were not fixed. This data was developed using the same antibody clone with 98077-1-PBS in a different storage buffer formulation.

  • Flow cytometry (FC) experiment of mouse thymocytes using Anti-Mouse CD155/PVR Rabbit Recombinant Antibody (98077-1-RR)

    FC experiment of mouse thymocytes using 98077-1-RR (same clone as 98077-1-PBS)

    1x10^6 mouse thymocytes were surface stained with 0.25 ug Anti-Mouse CD155/PVR Rabbit Recombinant Antibody (98077-1-RR, Clone:240731B1) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were not fixed. This data was developed using the same antibody clone with 98077-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98077-1-RR

    Affinity and Kinetic Characterization of 98077-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98077-1-RR against Mouse CD155/PVR were performed. The affinity constant is 0.649 nM.

Geprüfte Anwendungen

Produktinformation

98077-1-PBS bindet in FC CD155/PVR und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name poliovirus receptor
Berechnetes Molekulargewicht45 kDa
GenBank-ZugangsnummerNM_027514.2
Gene symbol CD155/PVR
Gene ID (NCBI) 52118
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C.

Hintergrundinformationen

CD155, also known as the poliovirus receptor (PVR) or Necl-5, is one of the nectin-like family members, belonging to the Ca2+ independent immunoglobulin superfamily (IgSF) in cell adhesion molecules (PMID: 37660884). CD155 is a type I transmembrane protein composed of three extracellular immunoglobulin-like domains, a transmembrane domain, and a cytoplasmic tail. It is involved in cell-to-cell and cell-to-ECM adhesion (PMID: 32019260; 11437656). CD155 acts as a ligand for immune receptors, including TIGIT, CD96 and CD226, which are expressed on T cells and NK cells. CD155 interacts with these receptors to modulate immune responses, such as T cell activation and NK cell-mediated cytotoxicity (PMID: 37660884). CD155 serves as the entry receptor for poliovirus and thereby mediates susceptibility to poliovirus infection (PMID: 15034010).