CD157 Rekombinanter Antikörper

CD157 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241424H5

Kat-Nr. : 98146-1-RR

Synonyme

BST 1, Bone marrow stromal antigen 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, ADP-ribosyl cyclase 2, ADP ribosyl cyclase 2

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  FC experiment of human peripheral blood leukocytes using 98146-1-RR

  1x10^6 human peripheral blood leukocytes were surface stained with 0.15 ug Anti-Human CD157 Rabbit Recombinant Antibody (98146-1-RR, Clone: 241424H5), or Isotype Control and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to fixing and staining. Cells were not fixed.

• 

  FC experiment of human peripheral blood leukocytes using 98146-1-RR

  1x10^6 human peripheral blood leukocytes were surface stained with 0.15 ug Anti-Human CD157 Rabbit Recombinant Antibody (98146-1-RR, Clone: 241424H5) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to fixing and staining. Cells were not fixed.

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  Affinity and Kinetic Characterization of 98146-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98146-1-RR against Human CD157 were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: human peripheral blood leukocytes

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98146-1-RR bindet in FC CD157 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: bone marrow stromal cell antigen 1
• Berechnetes Molekulargewicht: 318 aa, 36 kDa
• GenBank-Zugangsnummer: BC012095
• Gene symbol: CD157
• Gene ID (NCBI): 683
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

CD157, also known as bone marrow stromal cell antigen 1 (BST-1), or ADP-ribosyl cyclase 2, is a glycosyl phosphotidylinositol-anchored protein that stimulates pre-B-cell growth and has adenosine diphosphate (ADP)-ribosyl cyclase and cyclic ADP-ribose (cADPR) hydrolase activity (PMID: 9473467, 11866528). The two enzymatic activities are responsible for the synthesis and hydrolysis of cADPR, a novel second messenger of calcium release from intracellular calcium stores.