CD16 Rekombinanter Antikörper
CD16 Rekombinant Antikörper für FC
Wirt / Isotyp
Maus / IgG2a
Getestete Reaktivität
Affe, human, nicht-humane Primaten
Anwendung
FC
Konjugation
FITC Plus Fluorescent Dye
CloneNo.
3G8
Kat-Nr. : FITC-65612
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in FC | human peripheral blood leukocytes |
Empfohlene Verdünnung
Anwendung | Verdünnung |
---|---|
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood. | |
Sample-dependent, check data in validation data gallery |
Produktinformation
FITC-65612 bindet in FC CD16 und zeigt Reaktivität mit Affe, human, nicht-humane Primaten
Getestete Reaktivität | Affe, human, nicht-humane Primaten |
Wirt / Isotyp | Maus / IgG2a |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | k.A. |
Vollständiger Name | Fc fragment of IgG, low affinity IIIa, receptor (CD16a) |
Berechnetes Molekulargewicht | 254 aa, 29 kDa |
GenBank-Zugangsnummer | BC017865 |
Gene symbol | CD16a |
Gene ID (NCBI) | 2214 |
Konjugation | FITC Plus Fluorescent Dye |
Excitation/Emission maxima wavelengths | 495 nm / 524 nm |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS with 0.09% sodium azide and 0.5% BSA |
Lagerungsbedingungen | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Hintergrundinformationen
CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B. Clone 3G8 recognizes both the CD16a and CD16b (PMID: 7592758).
Protokolle
PRODUKTSPEZIFISCHE PROTOKOLLE | |
---|---|
FC protocol for FITC Plus CD16 antibody FITC-65612 | Download protocol |
STANDARD-PROTOKOLLE | |
---|---|
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |