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CD163 Rekombinanter Antikörper

CD163 Rekombinant Antikörper für Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test

Konjugation

Unkonjugiert

CloneNo.

240233G5

Kat-Nr. : 83285-2-PBS

Synonyme

M130, sCD163

Filter:
  • Sandwich ELISA standard curve of MP00326-3

    Sandwich ELISA standard curve of MP00326-3

    Sandwich ELISA standard curve of MP00326-3, mouse CD163 Recombinant Matched Antibody Pair - PBS only. 83285-1-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard: Eg0794. 83285-2-PBS was HRP conjugated as the detection antibody. Range: 78.1-5000 pg/mL..

  • Sample test of MP00326-3

    Sample test of MP00326-3

    For the mouse lung supernatant cultured for 3 days, the mean mouse CD163 concentration was determined to be 154.4 pg/mL in ConA stimulated mouse lung supernatant.

  • Sample test of MP00326-3

    Sample test of MP00326-3

    Serum of sixteen mice was measured. The CD163 concentration of detected samples was determined to be 92.2 ng/mL with a range of 46.2-146.5 ng/mL.

Geprüfte Anwendungen

Produktinformation

83285-2-PBS bindet in Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test CD163 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CD163 fusion protein Eg0794
Vollständiger Name CD163 antigen
Berechnetes Molekulargewicht121 kDa
GenBank-ZugangsnummerNM_053094.2
Gene symbol Cd163
Gene ID (NCBI) 93671
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD163, also known as M130, is a membrane glycoprotein that belongs to the scavenger receptor superfamily (PMID: 8370408). It is an acute phase-regulated and signal-inducing macrophage protein expressed exclusively in monocytes and tissue macrophages (PMID: 11196644). CD163 mediates endocytosis of haptoglobin-haemoglobin complexes (PMID: 11196644). The uptake of haptoglobin by macrophages contributes to the recycling of iron and also to the inflammatory response (PMID: 22900885). Soluble CD163 (sCD163), as a result of ectodomain shedding during inflammatory activation of macrophages, circulates in blood and has been suggested as a plasma/serum marker for macrophage activity (PMID: 12570164).