CD163 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

CD163 Polyklonal Antikörper für IF-P

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF-P

Konjugation

CoraLite®594 Fluorescent Dye

Publikationen(2)

Kat-Nr. : CL594-16646

Synonyme

CD163, CD163 molecule, Hemoglobin scavenger receptor, M130, MM130, sCD163

---

• 

  IF Staining of human tonsillitis using CL594-16646

  Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite®594 CD163 antibody (CL594-16646) at dilution of 1:200.

• 

  IF Staining of human tonsillitis using CL594-16646

  Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite®594 CD163 antibody (CL594-16646) at dilution of 1:200.

• 

  IF Staining of human liver using CL594-16646

  Immunofluorescent analysis of (4% PFA) fixed human liver tissue using CoraLite®594 CD163 antibody (CL594-16646) at dilution of 1:200.

• 

  IF Staining of human liver using CL594-16646

  Immunofluorescent analysis of (4% PFA) fixed human liver tissue using CoraLite®594 CD163 antibody (CL594-16646) at dilution of 1:200.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in IF-P: humanes Tonsillitisgewebe, humanes Lebergewebe

Empfohlene Verdünnung

• Immunfluoreszenz (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 1 publications below
• IF: See 1 publications below

Produktinformation

CL594-16646 bindet in WB, IF-P CD163 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CD163 fusion protein Ag10029
• Vollständiger Name: CD163 molecule
• Berechnetes Molekulargewicht: 1156 aa, 125 kDa
• GenBank-Zugangsnummer: BC051281
• Gene symbol: CD163
• Gene ID (NCBI): 9332
• Konjugation: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA
• Lagerungsbedingungen: Bei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD163 is a transmembrane protein which belongs to the scavenger receptor cysteine-rich (SRCR) superfamily. This protein is a scavenger receptor for the hemoglobin-haptoglobin complex and is a marker for monocytes and macrophages. Soluble CD163 (sCD163), as a result of ectodomain shedding during inflammatory activation of macrophages, circulates in blood and has been suggested as a plasma/serum marker for macrophage activity.

Publikationen

Species	Application	Title
human	IF	Front Immunol; Identification of CD101 in Glioma: A Novel Prognostic Indicator Expressed on M2 Macrophages.; Authors - Yuyang Liu
human	WB	Phytomedicine; Ginsenoside RK3 inhibits glioblastoma by modulating macrophage M2 polarization via the PPARG/CCL2 axis; Authors - Haiying Zhang