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CD164 Rekombinanter Antikörper

CD164 Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242986G5

Kat-Nr. : 85723-4-PBS

Synonyme

Endolyn, MGC-24, MGC-24v, MUC-24, Multi-glycosylated core protein 24

Filter:
  • Western Blot (WB) analysis of mouse liver tissue using CD164 Recombinant antibody (85723-4-RR)

    WB analysis of mouse liver using 85723-4-RR (same clone as 85723-4-PBS)

    mouse liver tissue was subjected to SDS PAGE followed by western blot with 85723-4-RR (CD164 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85723-4-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of RM-1 cells using CD164 Recombinant antibody (85723-4-RR)

    IF Staining of RM-1 using 85723-4-RR (same clone as 85723-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed RM-1 cells using CD164 antibody (85723-4-RR, Clone: 242986G5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 85723-4-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85723-4-PBS bindet in WB, IF/ICC, Indirect ELISA CD164 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CD164 fusion protein Eg2645
Vollständiger Name CD164 antigen
Berechnetes Molekulargewicht21 kDa
Beobachtetes Molekulargewicht80 kDa
GenBank-ZugangsnummerNM_016898.2
Gene symbol Cd164
Gene ID (NCBI) 53599
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play 2 key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor (PMID: 9680353)(PMID: 17077324). Sialomucin CD164 (MUC-24), also referred to multi-glycosylated core protein 24 (MGC24), is known to function as a receptor that regulates stem cell localization to the bone marrow. CD164 may play a key role in hematopoiesis by facilitating the adhesion of CD34+ cells to the stroma and by negatively regulating CD34+CD38(lo/-) cell proliferation. Important role of CD164 in in prostate cancer metastasis, promoting myogenesis and regulating myoblast migration so far have been revealed (PMID: 9763543)(PMID: 16859559)(PMID: 17077324).