CD16b Rekombinanter Antikörper

CD16b Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241713E3

Kat-Nr. : 98192-1-PBS

Synonyme

CD16, FCGR3B, 241713E3, Fc gamma RIII, Fc gamma RIII beta

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  FC experiment of human peripheral blood leukocytes using 98192-1-RR (same clone as 98192-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD16b Rabbit Recombinant Antibody (98192-1-RR, Clone:241713E3) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-conjugated Goat Anti-Rabbit IgG. Cells were not fixed. This data was developed using the same antibody clone with 98192-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human peripheral blood leukocytes using 98192-1-RR (same clone as 98192-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD16b Rabbit Recombinant Antibody (98192-1-RR, Clone:241713E3) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were not fixed. This data was developed using the same antibody clone with 98192-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98192-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98192-1-RR against Human CD16b were performed. The affinity constant is 2.36 nM.

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Geprüfte Anwendungen

Produktinformation

98192-1-PBS bindet in FC CD16b und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD16b fusion protein Eg2487
• Vollständiger Name: Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
• Gene symbol: FCGR3B
• Gene ID (NCBI): 2215
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CD16 is a low affinity Fc receptor. It has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and FCGR3B. In humans, FcγRIIIa/CD16a is a type I transmembrane receptor expressed on macrophages and NK cells. FcγRIIIb/CD16b is a GPI-linked Fc-receptor highly expressed on neutrophils. The two proteins differ by only four amino acid residues in the mature proteins (PMID: 30361439).