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CD177 Polyklonaler Antikörper

CD177 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 18264-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse bone marrow using CD177 Polyclonal antibody (18264-1-AP)

    WB analysis of mouse bone marrow using 18264-1-AP (same clone as 18264-1-PBS)

    mouse bone marrow tissue was subjected to SDS PAGE followed by western blot with 18264-1-AP (CD177 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18264-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

18264-1-PBS bindet in WB, Indirect ELISA CD177 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CD177 fusion protein Ag13146
Vollständiger Name CD177 molecule
Berechnetes Molekulargewicht 437 aa, 46 kDa
Beobachtetes Molekulargewicht100-130 kDa
GenBank-ZugangsnummerBC029167
Gene symbol CD177
Gene ID (NCBI) 57126
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD177, also known as NB1, HNA-2a or PRV-1, is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that belongs to the uPAR/CD59/Ly6 snake toxin superfamily (PMID: 17898576). It is expressed exclusively by neutrophils, neutrophilic metamyelocytes, and myelocytes (PMID: 17580308). CD177 interacts with β2 integrin CD11b/CD18 and CD11a/CD18, PECAM-1, and participates in neutrophil activation and transmigration (PMID: 17580308; 21193407). CD177 has been identified as a useful biomarker for myeloproliferative diseases (PMID: 17898576).