CD177 Rekombinanter Antikörper

CD177 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250745B9

Kat-Nr. : 86454-1-PBS

Synonyme

CD177 antigen

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  WB analysis of mouse bone marrow using 86454-1-RR (same clone as 86454-1-PBS)

  mouse bone marrow tissue was subjected to SDS PAGE followed by western blot with 86454-1-RR (Cd177 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86454-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

86454-1-PBS bindet in WB, Indirect ELISA CD177 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD177 fusion protein Eg2668
• Vollständiger Name: CD177 antigen
• Berechnetes Molekulargewicht: 87 kDa
• Beobachtetes Molekulargewicht: 130 kDa
• GenBank-Zugangsnummer: NM_026862.3
• Gene symbol: Cd177
• Gene ID (NCBI): 68891
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD177, also known as NB1, HNA-2a or PRV-1, is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that belongs to the uPAR/CD59/Ly6 snake toxin superfamily (PMID: 17898576). It is expressed exclusively by neutrophils, neutrophilic metamyelocytes, and myelocytes (PMID: 17580308). CD177 interacts with β2 integrin CD11b/CD18 and CD11a/CD18, PECAM-1, and participates in neutrophil activation and transmigration (PMID: 17580308; 21193407). CD177 has been identified as a useful biomarker for myeloproliferative diseases (PMID: 17898576).