CD19 Monoklonaler Antikörper

CD19 Monoklonal Antikörper für IF-Fro, FC

Wirt / Isotyp

Ratte / IgG2a, kappa

Getestete Reaktivität

Maus

Anwendung

IF-Fro, FC

Konjugation

Unkonjugiert

CloneNo.

1D3

Kat-Nr. : 65290-1-Ig

Synonyme

CD19 antigen, 1D3



Geprüfte Anwendungen

Erfolgreiche Detektion in IF-FroMausmilzgewebe
Erfolgreiche Detektion in FCMaus-Splenozyten

Empfohlene Verdünnung

AnwendungVerdünnung
Immunfluoreszenz (IF)-FROIF-FRO : 1:200-1:800
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

65290-1-Ig bindet in IF-Fro, FC CD19 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Ratte / IgG2a, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen Mouse CD19 Transfected Cell Line
Vollständiger Name CD19 antigen
GenBank-ZugangsnummerBC156767
Gene symbol Cd19
Gene ID (NCBI) 12478
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Affinitätsreinigung
Lagerungspuffer PBS with 0.09% sodium azide
LagerungsbedingungenStore at 2-8°C. Stable for one year after shipment.

Hintergrundinformationen

CD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily (PMID: 2472450). It is expressed by B cells and follicular dendritic cells. CD19 is up-regulated at the step of B-lineage commitment during the differentiation of the hematopoietic stem cell, it remains on during subsequent stages of differentiation until finally down-regulated during terminal differentiation into plasma cells (PMID: 8528044). CD19 is involved in B cell development, activation and differentiation. It is the dominant component for the signaling complex on B cells that includes CD21 (CR2), CD81 (TAPA-1) and CD225 and acts as a critical co-receptor for BCR signal transduction (PMID: 23210908).

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
IF protocol for CD19 antibody 65290-1-IgProtokoll herunterladen
FC protocol for CD19 antibody 65290-1-IgDownload protocol
STANDARD-PROTOKOLLE
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen