CD19 Rekombinanter Antikörper

CD19 Rekombinant Antikörper für FC

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

Kaninchen

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242570A11

Kat-Nr. : 98351-1-MR

Synonyme

CD19 molecule

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  FC experiment of rabbit splenocytes using 98351-1-MR

  1x10^6 rabbit splenocytes were surface stained with 0.25 ug Anti-Rabbit CD19 Mouse RecAb (98351-1-MR, Clone:242570A11) .or Mouse IgG2a Isotype Control (C1.18.4) (65208-1-Ig, Clone: C1.18.4)and PE-conjugated Goat Anti-Mouse IgG. Cells were then stained with Anti-Rabbit FITC-CD4. Cells were not fixed.

• 

  FC experiment of rabbit splenocytes using 98351-1-MR

  1x10^6 rabbit splenocytes were surface stained with 0.25 ug Anti-Rabbit CD19 Mouse RecAb (98351-1-MR, Clone:242570A11)(red).or Mouse IgG2a Isotype Control (C1.18.4) (65208-1-Ig, Clone: C1.18.4)and PE-conjugated Goat Anti-Mouse IgG(blue). Cells were not fixed.

• 

  FC experiment of rabbit splenocytes using 98351-1-MR

  1x10^6 rabbit splenocytes were surface stained with 0.25 ug Anti-Rabbit CD19 Mouse RecAb (98351-1-MR, Clone:242570A11).or Mouse IgG2a Isotype Control (C1.18.4) (65208-1-Ig, Clone: C1.18.4)and PE-conjugated Goat Anti-Mouse IgG. Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: rabbit splenocytes

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98351-1-MR bindet in FC CD19 und zeigt Reaktivität mit Kaninchen

• Getestete Reaktivität: Kaninchen
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD19 fusion protein Eg3526
• Vollständiger Name: CD19
• Gene symbol: CD19
• Gene ID (NCBI): 100345233
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

CD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily (PMID: 2472450). It is expressed by B cells and follicular dendritic cells. CD19 is up-regulated at the step of B-lineage commitment during the differentiation of the hematopoietic stem cell, it remains on during subsequent stages of differentiation until finally down-regulated during terminal differentiation into plasma cells (PMID: 8528044). CD19 is involved in B cell development, activation and differentiation. It is the dominant component for the signaling complex on B cells that includes CD21 (CR2), CD81 (TAPA-1) and CD225 and acts as a critical co-receptor for BCR signal transduction (PMID: 23210908).