CD1d Monoklonaler Antikörper

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• KD/KO Validated

CD1d Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1C12F1

Kat-Nr. : 66257-1-PBS

Synonyme

CD1A, CD1D, CD1d molecule, R3, R3G1

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  WB analysis of Jurkat using 66257-1-Ig (same clone as 66257-1-PBS)

  WB result of CD1D antibody (66257-1-Ig, 1:500) with si-Control and si-CD1D transfected Jurkat cells. This data was developed using the same antibody clone with 66257-1-PBS in a different storage buffer formulation.

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  WB analysis of human testis using 66257-1-Ig (same clone as 66257-1-PBS)

  human testis tissue were subjected to SDS PAGE followed by western blot with 66257-1-Ig (CD1D Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66257-1-PBS in a different storage buffer formulation.

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  IHC staining of human skin using 66257-1-Ig (same clone as 66257-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin tissue slide using 66257-1-Ig (CD1d antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 66257-1-PBS in a different storage buffer formulation.

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  IHC staining of human skin using 66257-1-Ig (same clone as 66257-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin tissue slide using 66257-1-Ig (CD1d antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 66257-1-PBS in a different storage buffer formulation.

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  IHC staining of human small intestine using 66257-1-Ig (same clone as 66257-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 66257-1-Ig (CD1d antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 66257-1-PBS in a different storage buffer formulation.

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  IHC staining of human small intestine using 66257-1-Ig (same clone as 66257-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 66257-1-Ig (CD1d antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 66257-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

66257-1-PBS bindet in WB, IHC, Indirect ELISA CD1d und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: CD1d fusion protein Ag11108
• Vollständiger Name: CD1d molecule
• Berechnetes Molekulargewicht: 335 aa, 38 kDa
• Beobachtetes Molekulargewicht: 40 kDa, 50-55 kDa
• GenBank-Zugangsnummer: BC027926
• Gene symbol: CD1D
• Gene ID (NCBI): 912
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD1d is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. CD1d is an antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on NKT cells. When activated, NKT cells rapidly produce Th1 and Th2 cytokines. The molecular weight of unglycosylated CD1d is 38 kDa, while glycosylated form of CD1d is 48-55 kDa.