CD2 Rekombinanter Antikörper

CD2 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241548A5

Kat-Nr. : 98193-1-PBS

Synonyme

241548A5, LFA-2, LFA-3 receptor, Ly-37, Lymphocyte antigen 37

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  FC experiment of mouse splenocytes using 98193-1-RR (same clone as 98193-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.15 ug Anti-Mouse CD2 Rabbit Recombinant Antibody (98193-1-RR, Clone: 241548A5) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-conjugated Goat Anti-Rabbit IgG. Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD19. Cells were not fixed. This data was developed using the same antibody clone with 98193-1-PBS in a different storage buffer formulation.

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  FC experiment of mouse splenocytes using 98193-1-RR (same clone as 98193-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.15 ug Anti-Mouse CD2 Rabbit Recombinant Antibody (98193-1-RR, Clone:241548A5) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue) and PE-conjugated Goat Anti-Rabbit IgG. Cells were not fixed. This data was developed using the same antibody clone with 98193-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98193-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98193-1-RR against Mouse CD2 were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

Produktinformation

98193-1-PBS bindet in FC CD2 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD2 fusion protein Eg1403
• Vollständiger Name: CD2 antigen
• Berechnetes Molekulargewicht: 38 kDa
• GenBank-Zugangsnummer: NM_013486.2
• Gene symbol: CD2
• Gene ID (NCBI): 12481
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CD2 is a cell surface glycoprotein present on a majority of thymocytes, all mature T cells and subset of NK cells but not on B lymphocytes. It is a pan T-cell marker. CD2 interacts with lymphocyte function-associated antigen (LFA-3/CD58) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.