CD200 Monoklonaler Antikörper

CD200 Monoklonal Antikörper für FC

Wirt / Isotyp

Ratte / IgG2a, kappa

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

OX90

Kat-Nr. : 65230-1-Ig

Synonyme

Cd200, CD200 antigen, Mox2, OX2

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  FC experiment of mouse splenocytes using 65230-1-Ig

  1x10^6 mouse splenocytes were surface stained with 1 ug Anti-Mouse CD200 (65230-1-Ig, Clone: OX90) and FITC anti-rat IgG2a Antibody at dilution 1:100 (red), or 1 ug Rat IgG2a Isotype Control (2A3) (65209-1-Ig, Clone: 2A3) and FITC anti-rat IgG2a Antibody at dilution 1:100 (blue). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using 65230-1-Ig

  1x10^6 mouse splenocytes were surface stained with 1 ug Anti-Mouse CD200 (65230-1-Ig, Clone: OX90) and FITC anti-rat IgG2a Antibody at dilution 1:100, or 1 ug Rat IgG2a Isotype Control (2A3) (65209-1-Ig, Clone: 2A3) and FITC anti-rat IgG2a Antibody at dilution 1:100. Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

65230-1-Ig bindet in FC CD200 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Ratte / IgG2a, kappa
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Mouse CD200-rat CD4 fusion protein
• Vollständiger Name: CD200 antigen
• GenBank-Zugangsnummer: BC051984
• Gene symbol: Cd200
• Gene ID (NCBI): 17470
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Stable for one year after shipment.

Hintergrundinformationen

CD200, also known as OX2, is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 3032785). It contains two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. CD200 is expressed on a variety of cell types, including thymocytes, B lymphocytes, a subset of T lymphocytes, follicular dendritic cells, neurons, and endothelial cells (PMID: 3032785; 10981966). CD200 binds to its receptor, CD200R, which is primarily expressed by myeloid and T cell lineage (PMID: 15187158). The CD200-CD200R interaction plays a role in immunosuppression and suppression of anti-tumor immune responses (PMID: 22020332).