CD209 Rekombinanter Antikörper

CD209 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

240907A2

Kat-Nr. : 84095-6-PBS

Synonyme

DC SIGN1, DC SIGN, C-type lectin domain family 4 member L, CLEC4L, CDSIGN

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  WB analysis of human placenta using 84095-6-RR (same clone as 84095-6-PBS)

  human placenta tissue was subjected to SDS PAGE followed by western blot with 84095-6-RR (CD209 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84095-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84095-6-RR

  Biolayer interferometry (BLl) kinetic assays of 84095-6-RR against Human CD209 were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

Produktinformation

84095-6-PBS bindet in WB, Indirect ELISA CD209 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Fusionsprotein
• Vollständiger Name: CD209 molecule
• Berechnetes Molekulargewicht: 404 aa, 45.7 kDa
• Beobachtetes Molekulargewicht: 48 kDa
• GenBank-Zugangsnummer: BC110615
• Gene symbol: CD209
• Gene ID (NCBI): 30835
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).