CD209 Rekombinanter Antikörper

CD209 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

240907A4

Kat-Nr. : 98156-1-RR

Synonyme

DC SIGN1, DC SIGN, C-type lectin domain family 4 member L, CLEC4L, CDSIGN

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  FC experiment of human monocyte-derived immature dendritic cells using 98156-1-RR

  1x10^6 human monocyte-derived immature dendritic cells were surface stained with 0.25 ug Anti-Human CD209 Rabbit Recombinant Antibody (98156-1-RR, Clone: 240907A4) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

• 

  Affinity and Kinetic Characterization of 98156-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98156-1-RR against Human CD209 were performed. The affinity constant is 1.94 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: human monocyte-derived immature dendritic cells

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98156-1-RR bindet in FC CD209 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Fusionsprotein
• Vollständiger Name: CD209 molecule
• Berechnetes Molekulargewicht: 404 aa, 45.7 kDa
• GenBank-Zugangsnummer: BC110615
• Gene symbol: CD209
• Gene ID (NCBI): 30835
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).