CD209 Rekombinanter Antikörper

CD209 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Biotin

CloneNo.

240907A4

Kat-Nr. : Biotin-FcA98156

Synonyme

240907A4, CDSIGN, CLEC4L, C-type lectin domain family 4 member L, DC SIGN

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  FC experiment of human monocyte-derived dendritic using Biotin-FcA98156

  1x10^6 human monocyte-derived dendritic cells were surface stained with 0.25 ug Biotin Anti-Human CD209 Rabbit RecAb (Biotin-FcA98156, Clone: 240907A4) (red) or 0.25 ug FcZero-rAb™ Biotin Rabbit IgG Isotype Control Recombinant Antibody (Biotin-FcA98136, Clone: 240953C9), and PE-conjugated streptavidin. Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: humane, aus Monozyten gewonnene dendritische Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

Biotin-FcA98156 bindet in FC CD209 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD209 fusion protein Eg0062
• Vollständiger Name: CD209 molecule
• Berechnetes Molekulargewicht: 404 aa, 45.7 kDa
• GenBank-Zugangsnummer: BC110615
• Gene symbol: CD209
• Gene ID (NCBI): 30835
• Konjugation: Biotin
• Excitation/Emission maxima wavelengths: -
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).