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CD21 Monoklonaler Antikörper

CD21 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1D9A3

Kat-Nr. : 66701-1-PBS

Synonyme

C3DR, CD21, Complement C3d receptor, Complement receptor type 2, CR2, EBV receptor, Epstein Barr virus receptor, SLEB9

Filter:
  • Western Blot (WB) analysis of human spleen tissue using CD21 Monoclonal antibody (66701-1-Ig)

    WB analysis of human spleen using 66701-1-Ig (same clone as 66701-1-PBS)

    human spleen tissue were subjected to SDS PAGE followed by western blot with 66701-1-Ig (CD21 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66701-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66701-1-PBS bindet in WB, Indirect ELISA CD21 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen CD21 fusion protein Ag18058
Vollständiger Name complement component (3d/Epstein Barr virus) receptor 2
Berechnetes Molekulargewicht 1092 aa, 119 kDa
Beobachtetes Molekulargewicht 150 kDa
GenBank-ZugangsnummerBC136394
Gene symbol CD21
Gene ID (NCBI) 1380
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD21, also known as complement receptor type 2 (CR2), complement C3d receptor, and Epstein-Barr virus receptor, is a transmembrane protein that contains a small cytoplasmic domain, a transmembrane region and an extracellular domain consisting of 15 tandem short consensus repeat sequences (PMID: 6230668; 2551147). It is expressed on B cells, follicular dendritic cells, thymocytes and a subset of peripheral T cells (PMID: 26119182). CD21 binds complement fragments C3d, C3dg and iC3b and acts as a receptor for the Epstein-Barr virus (PMID: 7753047). On B cells, together with CD19 and CD81, CD21 forms a complex that functions as a co-receptor to the BCR (PMID: 7542009). It is involved in B cells activation and functions.