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CD226 Monoklonaler Antikörper

CD226 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

7G7A4

Kat-Nr. : 67653-1-PBS

Synonyme

CD226, CD226 antigen, CD226 molecule, DNAM 1, DNAM1, DNAX accessory molecule 1, PTA1, TLiSA1

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  • Western Blot (WB) analysis of human peripheral blood platelets using CD226 Monoclonal antibody (67653-1-Ig)

    WB analysis of human peripheral blood platelets using 67653-1-Ig (same clone as 67653-1-PBS)

    human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 67653-1-Ig (CD226 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67653-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67653-1-PBS bindet in WB, Indirect ELISA CD226 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen CD226 fusion protein Ag12403
Vollständiger Name CD226 molecule
Berechnetes Molekulargewicht 336 aa, 39 kDa
Beobachtetes Molekulargewicht 65 kDa
GenBank-ZugangsnummerBC074787
Gene symbol CD226
Gene ID (NCBI) 10666
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383).