CD226 Rekombinanter Antikörper
CD226 Rekombinant Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
Maus
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
250384D8
Kat-Nr. : 86025-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
86025-1-PBS bindet in WB, Indirect ELISA CD226 und zeigt Reaktivität mit Maus
| Getestete Reaktivität | Maus |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | CD226 fusion protein Eg1588 |
| Vollständiger Name | CD226 antigen |
| Berechnetes Molekulargewicht | 39 kDa |
| Beobachtetes Molekulargewicht | 60-75 kDa |
| GenBank-Zugangsnummer | NM_178687.2 |
| Gene symbol | Cd226 |
| Gene ID (NCBI) | 225825 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
CD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes, and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383).

