CD226 Rekombinanter Antikörper

CD226 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

250384G1

Kat-Nr. : 98495-1-RR

Synonyme

CD226 antigen, Dnam-1 , Platelet and T-cell activation antigen 1, Pta1

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  FC experiment of mouse splenocytes using 98495-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD226 Rabbit RecAb (98495-1-RR, Clone: 250384G1) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Mouse CD8a. Cells were not fixed.

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  FC experiment of mouse splenocytes using 98495-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD226 Rabbit RecAb (98495-1-RR, Clone: 250384G1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98495-1-RR bindet in FC CD226 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD226 fusion protein Eg1588
• Vollständiger Name: CD226 antigen
• Berechnetes Molekulargewicht: 39 kDa
• GenBank-Zugangsnummer: NM_178687.2
• Gene symbol: Cd226
• Gene ID (NCBI): 225825
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

CD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383).