CD226 Rekombinanter Antikörper

CD226 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

CoraLite®700 Fluorescent Dye

CloneNo.

240673G4

Kat-Nr. : CL700-98002-2

Synonyme

240673G4, CD226 antigen, CD226 molecule, DNAM 1, DNAM1

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  FC experiment of human PBMCs using CL700-98002-2

  1x10^6 human PBMCs were surface stained with 5 ul CoraLite® Plus 488 Anti-Human CD3 (UCHT1) Mouse IgG2a Recombinant Antibody (CL488-65570, Clone: UCHT1), and 5 ul CoraLite®700 Anti-Human CD226 Rabbit RecAb (CL700-98002-2, Clone: 240673G4) or Isotype Control. Cells were not fixed.

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  FC experiment of human PBMCs using CL700-98002-2

  1x10^6 human PBMCs were surface stained with 5 ul CoraLite®700 Anti-Human CD226 Rabbit RecAb (CL700-98002-2, Clone: 240673G4) (red) or Isotype Control (blue). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: humane PBMCs

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

CL700-98002-2 bindet in FC CD226 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD226 fusion protein Eg0027
• Vollständiger Name: CD226 molecule
• Berechnetes Molekulargewicht: 336 aa, 39 kDa
• GenBank-Zugangsnummer: BC074787
• Gene symbol: CD226
• Gene ID (NCBI): 10666
• Konjugation: CoraLite®700 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 702 nm / 723 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383).