CD229/SLAMF3 Rekombinanter Antikörper

CD229/SLAMF3 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242312D12

Kat-Nr. : 98274-1-PBS

Synonyme

Lymphocyte antigen 9, Ly-9, Ly9, Cell surface molecule Ly-9, CD229

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  FC experiment of mouse splenocytes using 98274-1-RR (same clone as 98274-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD229/SLAMF3 Rabbit Recombinant Antibody (98274-1-RR, Clone: 242312D12) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (blue). Cells were not fixed. This data was developed using the same antibody clone with 98274-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98274-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98274-1-RR against Mouse CD229/SLAMF3 were performed. The affinity constant is 2.29 nM.

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Geprüfte Anwendungen

Produktinformation

98274-1-PBS bindet in FC CD229/SLAMF3 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: lymphocyte antigen 9
• Berechnetes Molekulargewicht: 73 kDa
• GenBank-Zugangsnummer: NM_001277968.1
• Gene symbol: Ly9
• Gene ID (NCBI): 17085
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Signaling lymphocytic activation molecule 3 (SLAMF3), also known as CD229 or Ly9, is a type I transmembrane glycoprotein that belongs to the SLAM family receptors (PMID: 10970093; 15905546). It is composed of an extracellular region, which consists of four Ig-like domains, a transmembrane region, and a cytoplasmic tail, which includes two immunoreceptor tyrosine-based signaling motifs (ITSMs) and other tyrosine residues that act as binding sites for the SH2 structural domains (PMID: 8537117; 11369645; 38626547). SLAMF3 is mainly expressed in immune cells, such as T, B, and natural killer cells, and it is involved in the fundamental activation and suppression of these immune cells, as well as the regulation of complex immune networks (PMID: 38626547).