CD229/SLAMF3 Rekombinanter Antikörper

CD229/SLAMF3 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

APC Fluorescent Dye

CloneNo.

242312D12

Kat-Nr. : APC-FcA98274

Synonyme

CD229, Cell surface molecule Ly-9, Ly9, Ly-9, Lymphocyte antigen 9

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  FC experiment of mouse splenocytes using APC-FcA98274

  1x10^6 mouse splenocytes were surface stained with 0.1 ug APC Anti-Mouse CD229/SLAMF3 Rabbit RecAb (APC-FcA98274, Clone: 242312D12) (red) or 0.1 ug APC Rabbit IgG Isotype Control RecAb (APC-FcA98136, Clone: 240953C9). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

APC-FcA98274 bindet in FC CD229/SLAMF3 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD229/SLAMF3 fusion protein Eg1586
• Vollständiger Name: lymphocyte antigen 9
• Berechnetes Molekulargewicht: 73 kDa
• GenBank-Zugangsnummer: NM_001277968.1
• Gene symbol: Ly9
• Gene ID (NCBI): 17085
• Konjugation: APC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 660 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

Signaling lymphocytic activation molecule 3 (SLAMF3), also known as CD229 or Ly9, is a type I transmembrane glycoprotein that belongs to the SLAM family receptors (PMID: 10970093; 15905546). It is composed of an extracellular region, which consists of four Ig-like domains, a transmembrane region, and a cytoplasmic tail, which includes two immunoreceptor tyrosine-based signaling motifs (ITSMs) and other tyrosine residues that act as binding sites for the SH2 structural domains (PMID: 8537117; 11369645; 38626547). SLAMF3 is mainly expressed in immune cells, such as T, B, and natural killer cells, and it is involved in the fundamental activation and suppression of these immune cells, as well as the regulation of complex immune networks (PMID: 38626547).