CD25/IL-2RA Rekombinanter Antikörper

CD25/IL-2RA Rekombinant Antikörper für FC

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

Affe, human, nicht-humane Primaten

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

BC96

Kat-Nr. : 65620-1-PBS

Synonyme

CD25, BC96, IL 2 RA, IL 2 receptor subunit alpha, IL 2R subunit alpha

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  FC experiment of human PBMCs using 65620-1-MR (same clone as 65620-1-PBS)

  1x10^6 PHA treated human PBMCs were surface stained with 0.25 ug Anti-Human CD25 (BC96) Mouse IgG2a Recombinant Antibody (65620-1-MR, Clone: BC96) (red) or Mouse IgG2a Isotype Control (blue), and PE-conjugated Goat Anti-Mouse IgG. 1x10^6 untreated human PBMCs were surface stained with 0.25 ug Anti-Human CD25 (BC96) Mouse IgG2a Recombinant Antibody (65620-1-MR, Clone: BC96) and PE-conjugated Goat Anti-Mouse IgG (black, dashed). Cells were not fixed. This data was developed using the same antibody clone with 65620-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

65620-1-PBS bindet in FC CD25/IL-2RA und zeigt Reaktivität mit Affe, human, nicht-humane Primaten

• Getestete Reaktivität: Affe, human, nicht-humane Primaten
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: interleukin 2 receptor, alpha
• Berechnetes Molekulargewicht: 272 aa, 31 kDa
• GenBank-Zugangsnummer: BC156627
• Gene symbol: IL2RA
• Gene ID (NCBI): 3559
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Proliferation of T lymphocytes is triggered by the interaction of IL-2 with its specific receptor following T lymphocyte activation. The receptor for IL-2 has three forms, generated by different combinations of three different proteins, the alpha chain (IL-2R alpha), the beta chain (IL-2R beta), and the gamma chain (IL-2R gamma) (PMID: 8476561). IL-2R alpha (also known as CD25) is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. CD25 is also found on natural CD4+Foxp3+ Treg cells and a subset of human CD4+ memory T cells (PMID: 22585674).