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TWEAKR/CD266 Rekombinanter Antikörper

TWEAKR/CD266 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

240991C5

Kat-Nr. : 98125-1-PBS

Synonyme

CD266, TNFRSF12A, TweakR, 240991C5, APO3L

Filter:
  • Flow cytometry (FC) experiment of HT-1080 cells using Anti-Human TWEAKR/CD266 Rabbit Recombinant Antibod (98125-1-RR)

    FC experiment of HT-1080 using 98125-1-RR (same clone as 98125-1-PBS)

    1x10^6 HT-1080 cells were surface stained with 0.25 ug Anti-Human TWEAKR Rabbit Recombinant Antibody (98125-1-RR, Clone: 240991C5) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98125-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98125-1-RR

    Affinity and Kinetic Characterization of 98125-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98125-1-RR against Human CD266 were performed. The affinity constant is 0.508 nM.

Geprüfte Anwendungen

Produktinformation

98125-1-PBS bindet in FC TWEAKR/CD266 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen TWEAKR/CD266 fusion protein Ag13823
Vollständiger Name tumor necrosis factor receptor superfamily, member 12A
Berechnetes Molekulargewicht 129 aa, 14 kDa
GenBank-ZugangsnummerBC002718
Gene symbol TWEAKR
Gene ID (NCBI) 51330
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C.

Hintergrundinformationen

TWEAKR (also known as CD266, FN14, TNFRSF12A) is a member of the TNF receptor superfamily which is activated by its ligand, the cytokine TWEAK (TNFSF12). TWEAKR is the smallest member of the TNFR superfamily. TWEAKR was first described as an FGF-inducible gene that played a role in fibroblast adhesion and migration. Subsequently, the induction of TWEAKR expression by other growth factors and/or upon tissue injury was observed in multiple cell types, including hepatocytes, endothelial cells, adipocytes, and cardiomyocytes. (PMID: 23073510, PMID: 24409185)