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CD2AP Rekombinanter Antikörper

CD2AP Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251428G2

Kat-Nr. : 86727-1-PBS

Synonyme

CD2 associated protein, CD2-associated protein, Mesenchyme-to-epithelium transition protein with SH3 domains 1, METS 1, Mets1

Filter:
  • Western Blot (WB) analysis of various lysates using CD2AP Recombinant monoclonal antibody (86727-1-RR)

    WB analysis using 86727-1-RR (same clone as 86727-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86727-1-RR (Cd2ap antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86727-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86727-1-RR

    Affinity and Kinetic Characterization of 86727-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86727-1-RR against Mouse CD2AP were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

86727-1-PBS bindet in WB, Indirect ELISA CD2AP und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CD2AP fusion protein Ag0622
Vollständiger Name CD2-associated protein
Berechnetes Molekulargewicht 637 aa, 70 kDa
Beobachtetes Molekulargewicht74 kDa
GenBank-ZugangsnummerBC157901
Gene symbol Cd2ap
Gene ID (NCBI) 12488
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD2 associated protein (CD2AP, also known as CMS) is a scaffolding molecule that acts as an adapter protein between membrane proteins and the actin cytoskeleton (PMID: 10339567). CD2AP also plays a role in epithelial cell junction formation and affects the pathogenesis of Alzheimer's disease (PMID: 22891260; 31440393). Its mutations are associated with sporadic nephrotic syndrome and focal segmental glomerulosclerosis (FSGS) (PMID: 17713465; 19131354).