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CD3 Delta Monoklonaler Antikörper

CD3 Delta Monoklonal Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3A12H2

Kat-Nr. : 60194-1-PBS

Synonyme

CD3D, 3A12H2, CD3-delta, T cell receptor T3 delta chain, T3D

Filter:
  • Western Blot (WB) analysis of jurkat cells using CD3 Delta Monoclonal antibody (60194-1-Ig)

    WB analysis of jurkat using 60194-1-Ig (same clone as 60194-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 60194-1-Ig (CD3 delta antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60194-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP50691-2

    Cytometric bead array standard curve of MP50691-2

    Cytometric bead array standard curve of MP50691-2, CD3D/CD3 Delta Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60194-1-PBS. Detection antibody: 60194-4-PBS. Standard:Ag10207. Range: 0.781-100 ng/mL.

Geprüfte Anwendungen

Produktinformation

60194-1-PBS bindet in WB, Cytometric bead array, Indirect ELISA CD3 Delta und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen CD3 Delta fusion protein Ag10207
Vollständiger Name CD3d molecule, delta (CD3-TCR complex)
Berechnetes Molekulargewicht 171 aa, 19 kDa
Beobachtetes Molekulargewicht 25 kDa
GenBank-ZugangsnummerBC070321
Gene symbol CD3 Delta
Gene ID (NCBI) 915
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells. CD3 delta/CD3D is a single-pass type I membrane protein which consists of an extracellular domain of 84 amino acids, a transmembrane region, and a cytoplasmic domain of 45 amino acids. Defects in CD3 delta are a cause of severe combined immunodeficiency.