CD3 Gamma Monoklonaler Antikörper

CD3 Gamma Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2E9G7

Kat-Nr. : 60347-1-PBS

Synonyme

CD3G, 2E9G7, CD3-gamma, T cell receptor T3 gamma chain, T3G

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  WB analysis using 60347-1-Ig (same clone as 60347-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60347-1-Ig (CD3 Gamma antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60347-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

60347-1-PBS bindet in WB, Indirect ELISA CD3 Gamma und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: CD3 Gamma fusion protein Ag15502
• Vollständiger Name: CD3g molecule, gamma (CD3-TCR complex)
• Berechnetes Molekulargewicht: 182 aa, 20 kDa
• Beobachtetes Molekulargewicht: 20-25 kDa
• GenBank-Zugangsnummer: BC113830
• Gene symbol: CD3 Gamma
• Gene ID (NCBI): 917
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells.