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CD30/TNFRSF8 Rekombinanter Antikörper

CD30/TNFRSF8 Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241710B9

Kat-Nr. : 84420-7-PBS

Synonyme

CD30, CD30L receptor, Lymphocyte activation antigen CD30, Tnfrsf8, Tumor necrosis factor receptor superfamily member 8

Filter:
  • Western Blot (WB) analysis of EL-4 cells using CD30/TNFRSF8 Recombinant monoclonal antibody (84420-7-RR)

    WB analysis of EL-4 using 84420-7-RR (same clone as 84420-7-PBS)

    EL-4 cells were subjected to SDS PAGE followed by western blot with 84420-7-RR (CD30/TNFRSF8 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84420-7-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse spleen tissue using CD30/TNFRSF8 Recombinant monoclonal antibody (84420-7-RR)

    IHC staining of mouse spleen using 84420-7-RR (same clone as 84420-7-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse spleen tissue slide using 84420-7-RR (CD30/TNFRSF8 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84420-7-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84420-7-PBS bindet in WB, IHC, Indirect ELISA CD30/TNFRSF8 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CD30/TNFRSF8 fusion protein Eg1307
Vollständiger Name tumor necrosis factor receptor superfamily, member 8
Berechnetes Molekulargewicht53kDa
Beobachtetes Molekulargewicht 105-120 kDa
GenBank-ZugangsnummerNM_009401.2
Gene symbol Tnfrsf8
Gene ID (NCBI) 21941
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD30, also known as TNFRSF8 or Ki-1, is a transmembrane glycoprotein belonging to the tumor necrosis factor receptor superfamily. It is composed of an extracellular domain with six cysteine-rich repeats, a transmembrane segment, and an intracellular domain (PMID: 1310894). CD30 is expressed on a small subset of activated T and B lymphocytes, and a variety of lymphoid neoplasms, with the highest expression in classical Hodgkin's lymphoma and anaplastic large cell lymphoma (PMID: 9826579; 28885612). The CD30 ligand (CD30L or CD153) is a type II transmembrane glycoprotein of the tumor necrosis factor ligand superfamily (PMID: 8701986). Signal transduction of CD30/CD30L utilizes signal transducers, TNFR-associated factors (TRAF1, 2, 3 and 5) (PMID: 9826579).